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A polyketide macrolactone synthase from the filamentous fungus Gibberella zeae
Resorcylic acid lactones represent a unique class of fungal polyketides and display a wide range of biological activities, such as nanomolar inhibitors of Hsp90 and MAP kinase. The biosynthesis of these compounds is proposed to involve two fungal polyketide synthases (PKS) that function collaborativ...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2359803/ https://ncbi.nlm.nih.gov/pubmed/18427109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800657105 |
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