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A polyketide macrolactone synthase from the filamentous fungus Gibberella zeae

Resorcylic acid lactones represent a unique class of fungal polyketides and display a wide range of biological activities, such as nanomolar inhibitors of Hsp90 and MAP kinase. The biosynthesis of these compounds is proposed to involve two fungal polyketide synthases (PKS) that function collaborativ...

詳細記述

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書誌詳細
主要な著者: Zhou, Hui, Zhan, Jixun, Watanabe, Kenji, Xie, Xinkai, Tang, Yi
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359803/
https://ncbi.nlm.nih.gov/pubmed/18427109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800657105
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