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Enzymatic Synthesis of Aromatic Polyketides Using PKS4 from Gibberella fujikuroi

Iterative fungal polyketide synthases (PKSs) use a unique set of biochemical rules in the synthesis of complex polyketides. These rules dictate polyketide starter unit selection, chain length control, and post-PKS processing. We have demonstrated the E. coli expression and reconstitution of an itera...

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Detalhes bibliográficos
Main Authors: Ma, Suzanne M., Zhan, Jixun, Watanabe, Kenji, Xie, Xinkai, Zhang, Wenjun, Wang, Clay C., Tang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528842/
https://ncbi.nlm.nih.gov/pubmed/17696354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja074865p
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