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Structural basis for binding specificity between subclasses of modular polyketide synthase docking domains
Bacterial type I polyketide synthases assemble structurally diverse natural products of significant clinical value from simple metabolic building blocks. The synthesis of these compounds occurs in a processive fashion along a large multi-protein complex. Transfer of the acyl intermediate across inte...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2853223/ https://ncbi.nlm.nih.gov/pubmed/19146481 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb8002607 |
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