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Structural basis for binding specificity between subclasses of modular polyketide synthase docking domains

Bacterial type I polyketide synthases assemble structurally diverse natural products of significant clinical value from simple metabolic building blocks. The synthesis of these compounds occurs in a processive fashion along a large multi-protein complex. Transfer of the acyl intermediate across inte...

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Sonraí Bibleagrafaíochta
Main Authors: Buchholz, Tonia J., Geders, Todd W., Bartley, Frank E., Reynolds, Kevin A., Smith, Janet L., Sherman, David H.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853223/
https://ncbi.nlm.nih.gov/pubmed/19146481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb8002607
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