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Functional dissection of a multimodular polypeptide of the pikromycin polyketide synthase into monomodules using a matched pair of heterologous docking domains
The pikromyin polyketide synthase (PKS) in Streptomyces venezulae is comprised of a loading module and 6 extension modules which generate the corresponding 14-membered macrolactone product. PikAI is a multimodular component of this PKS and houses both the loading domain and the first two extension m...
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| Publicado no: | Chembiochem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4652847/ https://ncbi.nlm.nih.gov/pubmed/19437523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.200900098 |
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