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Portability and Structure of the Four-Helix Bundle Docking Domains of trans-Acyltransferase Modular Polyketide Synthases

The polypeptides of multimodular polyketide synthases self-assemble into biosynthetic factories. While the docking domains that mediate the assembly of cis-acyltransferase polyketide synthase polypeptides are well-studied, those of the more recently discovered trans-acyltransferase polyketide syntha...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Zeng, Jia, Wagner, Drew T., Zhang, Zhicheng, Moretto, Luisa, Addison, Janci D., Keatinge-Clay, Adrian T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460766/
https://ncbi.nlm.nih.gov/pubmed/27362945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00345
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