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An in vitro platform for engineering and harnessing modular polyketide synthases
To harness the synthetic power of modular polyketide synthases (PKSs), many aspects of their biochemistry must be elucidated. A robust platform to study these megadalton assembly lines has not yet been described. Here, we in vitro reconstitute the venemycin PKS, a short assembly line that generates...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6941969/ https://ncbi.nlm.nih.gov/pubmed/31900404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13811-0 |
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