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Crystal Structure of the Erythromycin Polyketide Synthase Dehydratase
The dehydratases (DHs) of modular polyketide synthases (PKSs) catalyze dehydrations that occur frequently in the biosynthesis of complex polyketides, yet little is known about them structurally or mechanistically. Here, the structure of a DH domain, isolated from the fourth module of the erythromyci...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3496180/ https://ncbi.nlm.nih.gov/pubmed/18952099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.09.084 |
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