Načítá se...

Substrate Structure-Activity Relationships Guide Rational Engineering of Modular Polyketide Synthase Ketoreductases

Modular polyketide synthase ketoreductases can set two chiral centers through a single reduction. To probe the basis of stereocontrol, a structure-activity relationship study was performed with three α-methyl, β-ketothioester substrates and four ketoreductases. Since interactions with the β-ketoacyl...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Chem Commun (Camb)
Hlavní autoři: Bailey, Constance B., Pasman, Marjolein E., Keatinge-Clay, Adrian T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690787/
https://ncbi.nlm.nih.gov/pubmed/26568113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cc07315d
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!