ロード中...

Substrate Structure-Activity Relationships Guide Rational Engineering of Modular Polyketide Synthase Ketoreductases

Modular polyketide synthase ketoreductases can set two chiral centers through a single reduction. To probe the basis of stereocontrol, a structure-activity relationship study was performed with three α-methyl, β-ketothioester substrates and four ketoreductases. Since interactions with the β-ketoacyl...

詳細記述

保存先:
書誌詳細
出版年:Chem Commun (Camb)
主要な著者: Bailey, Constance B., Pasman, Marjolein E., Keatinge-Clay, Adrian T.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690787/
https://ncbi.nlm.nih.gov/pubmed/26568113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cc07315d
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!