Laddar...
Substrate Structure-Activity Relationships Guide Rational Engineering of Modular Polyketide Synthase Ketoreductases
Modular polyketide synthase ketoreductases can set two chiral centers through a single reduction. To probe the basis of stereocontrol, a structure-activity relationship study was performed with three α-methyl, β-ketothioester substrates and four ketoreductases. Since interactions with the β-ketoacyl...
Sparad:
| I publikationen: | Chem Commun (Camb) |
|---|---|
| Huvudupphovsmän: | , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2015
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4690787/ https://ncbi.nlm.nih.gov/pubmed/26568113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cc07315d |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|