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The LINKS motif zippers trans-acyltransferase polyketide synthase assembly lines into a biosynthetic megacomplex

Polyketides such as the clinically-valuable antibacterial agent mupirocin are constructed by architecturally-sophisticated assembly lines known as trans-acyltransferase polyketide synthases. Organelle-sized megacomplexes composed of several copies of trans-acyltransferase polyketide synthase assembl...

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Detalhes bibliográficos
Publicado no:J Struct Biol
Main Authors: Gay, Darren C., Wagner, Drew T., Meinke, Jessica L., Zogzas, Charles E., Gay, Glen R., Keatinge-Clay, Adrian T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4738151/
https://ncbi.nlm.nih.gov/pubmed/26724270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2015.12.011
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