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Structural and Functional Trends in Dehydrating Bimodules from trans-Acyltransferase Polyketide Synthases

In an effort to uncover the structural motifs and biosynthetic logic of the relatively uncharacterized trans-acyltransferase polyketide synthases, we have begun the dissection of the enigmatic dehydrating bimodules common in these enzymatic assembly lines. We report the 1.98 Å-resolution structure o...

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Detalhes bibliográficos
Publicado no:Structure
Main Authors: Wagner, Drew T., Zeng, Jia, Bailey, Constance B., Gay, Darren C., Yuan, Fang, Manion, Hannah R., Keatinge-Clay, Adrian T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553570/
https://ncbi.nlm.nih.gov/pubmed/28625788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.05.011
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