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Wnt signaling arrests effector T cell differentiation and generates CD8(+) memory stem cells
Self-renewing cell populations such as hematopoietic stem cells and memory B and T lymphocytes might be regulated by shared signaling pathways1. Wnt/β-catenin is an evolutionarily conserved pathway that promotes hematopoietic stem cell self-renewal and multipotency by limiting stem cell proliferatio...
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| 主要な著者: | , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2707501/ https://ncbi.nlm.nih.gov/pubmed/19525962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.1982 |
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