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Activity of SQ641, a Capuramycin Analog, in a Murine Model of Tuberculosis
New delivery vehicles and routes of delivery were developed for the capuramycin analogue SQ641. While this compound has remarkable in vitro potency against Mycobacterium tuberculosis, it has low solubility in water and poor intracellular activity. We demonstrate here that SQ641 dissolved in the wate...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2704676/ https://ncbi.nlm.nih.gov/pubmed/19414567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00366-09 |
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