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Kinetic control of negative feedback regulators of NF-κB/RelA determines their pathogen- and cytokine-receptor signaling specificity
Mammalian signaling networks contain an abundance of negative feedback regulators that may have overlapping (“fail-safe”) or specific functions. Within the NF-κB signaling module, IκBα is known as a negative feedback regulator, but the newly characterized inhibitor IκBδ is also inducibly expressed i...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2701028/ https://ncbi.nlm.nih.gov/pubmed/19487661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812367106 |
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