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Identification of Oxadiazoles as New Drug Leads for the Control of Schistosomiasis

Treatment for schistosomiasis, which is responsible for hundreds of thousands of deaths annually, depends almost exclusively on praziquantel. Hundreds of millions of people are treated annually with praziquantel and drug resistant parasites are likely to evolve. Phosphinic amides and oxadiazole 2-ox...

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Bibliografiske detaljer
Main Authors: Sayed, Ahmed A., Simeonov, Anton, Thomas, Craig J., Inglese, James, Austin, Christopher P., Williams, David L.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700043/
https://ncbi.nlm.nih.gov/pubmed/18345010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1737
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