Quantitative High-Throughput Screen Identifies Inhibitors of the Schistosoma mansoni Redox Cascade

Schistosomiasis is a tropical disease associated with high morbidity and mortality, currently affecting over 200 million people worldwide. Praziquantel is the only drug used to treat the disease, and with its increased use the probability of developing drug resistance has grown significantly. The Sc...

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Bibliografiske detaljer
Main Authors: Simeonov, Anton, Jadhav, Ajit, Sayed, Ahmed A., Wang, Yuhong, Nelson, Michael E., Thomas, Craig J., Inglese, James, Williams, David L., Austin, Christopher P.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217675/
https://ncbi.nlm.nih.gov/pubmed/18235848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000127
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