Quantitative High-Throughput Screen Identifies Inhibitors of the Schistosoma mansoni Redox Cascade

Schistosomiasis is a tropical disease associated with high morbidity and mortality, currently affecting over 200 million people worldwide. Praziquantel is the only drug used to treat the disease, and with its increased use the probability of developing drug resistance has grown significantly. The Sc...

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Detalhes bibliográficos
Main Authors: Simeonov, Anton, Jadhav, Ajit, Sayed, Ahmed A., Wang, Yuhong, Nelson, Michael E., Thomas, Craig J., Inglese, James, Williams, David L., Austin, Christopher P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217675/
https://ncbi.nlm.nih.gov/pubmed/18235848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000127
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