Quantitative High-Throughput Screen Identifies Inhibitors of the Schistosoma mansoni Redox Cascade

Schistosomiasis is a tropical disease associated with high morbidity and mortality, currently affecting over 200 million people worldwide. Praziquantel is the only drug used to treat the disease, and with its increased use the probability of developing drug resistance has grown significantly. The Sc...

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Autori principali: Simeonov, Anton, Jadhav, Ajit, Sayed, Ahmed A., Wang, Yuhong, Nelson, Michael E., Thomas, Craig J., Inglese, James, Williams, David L., Austin, Christopher P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2008
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217675/
https://ncbi.nlm.nih.gov/pubmed/18235848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000127
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