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Identification of Oxadiazoles as New Drug Leads for the Control of Schistosomiasis

Treatment for schistosomiasis, which is responsible for hundreds of thousands of deaths annually, depends almost exclusively on praziquantel. Hundreds of millions of people are treated annually with praziquantel and drug resistant parasites are likely to evolve. Phosphinic amides and oxadiazole 2-ox...

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Hlavní autoři: Sayed, Ahmed A., Simeonov, Anton, Thomas, Craig J., Inglese, James, Austin, Christopher P., Williams, David L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700043/
https://ncbi.nlm.nih.gov/pubmed/18345010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1737
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