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Frequency-modulated nuclear localization bursts coordinate gene regulation

In yeast, the transcription factor Crz1 is dephosphorylated and translocates into the nucleus in response to extracellular calcium. Using time-lapse microscopy, we found that Crz1 exhibited short bursts of nuclear localization (∼2 minutes) that occurred stochastically in individual cells and propaga...

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Autors principals: Cai, Long, Dalal, Chiraj K., Elowitz, Michael B.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695983/
https://ncbi.nlm.nih.gov/pubmed/18818649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07292
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