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Combinatorial gene regulation by modulation of relative pulse timing

Studies of individual living cells have revealed that many transcription factors activate in dynamic, and often stochastic, pulses within the same cell. However, it has remained unclear whether cells might modulate the relative timing of these pulses to control gene expression. Here, using quantitat...

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Bibliographic Details
Published in:Nature
Main Authors: Lin, Yihan, Sohn, Chang Ho, Dalal, Chiraj K., Cai, Long, Elowitz, Michael B.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870307/
https://ncbi.nlm.nih.gov/pubmed/26466562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature15710
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