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Combinatorial gene regulation by modulation of relative pulse timing

Studies of individual living cells have revealed that many transcription factors activate in dynamic, and often stochastic, pulses within the same cell. However, it has remained unclear whether cells might modulate the relative timing of these pulses to control gene expression. Here, using quantitat...

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Bibliografische gegevens
Gepubliceerd in:Nature
Hoofdauteurs: Lin, Yihan, Sohn, Chang Ho, Dalal, Chiraj K., Cai, Long, Elowitz, Michael B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4870307/
https://ncbi.nlm.nih.gov/pubmed/26466562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature15710
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