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Frequency-modulated nuclear localization bursts coordinate gene regulation
In yeast, the transcription factor Crz1 is dephosphorylated and translocates into the nucleus in response to extracellular calcium. Using time-lapse microscopy, we found that Crz1 exhibited short bursts of nuclear localization (∼2 minutes) that occurred stochastically in individual cells and propaga...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2695983/ https://ncbi.nlm.nih.gov/pubmed/18818649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07292 |
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