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Modulation of transcriptional burst frequency by histone acetylation

Many mammalian genes are transcribed during short bursts of variable frequencies and sizes that substantially contribute to cell-to-cell variability. However, which molecular mechanisms determine bursting properties remains unclear. To probe putative mechanisms, we combined temporal analysis of tran...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Nicolas, Damien, Zoller, Benjamin, Suter, David M., Naef, Felix
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142243/
https://ncbi.nlm.nih.gov/pubmed/29915087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1722330115
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