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Modulation of transcriptional burst frequency by histone acetylation

Many mammalian genes are transcribed during short bursts of variable frequencies and sizes that substantially contribute to cell-to-cell variability. However, which molecular mechanisms determine bursting properties remains unclear. To probe putative mechanisms, we combined temporal analysis of tran...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Nicolas, Damien, Zoller, Benjamin, Suter, David M., Naef, Felix
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6142243/
https://ncbi.nlm.nih.gov/pubmed/29915087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1722330115
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