Enhancer Histone Acetylation Modulates Transcriptional Bursting Dynamics of Neuronal Activity-Inducible Genes

Neuronal activity-inducible gene transcription correlates with rapid and transient increases in histone acetylation at promoters and enhancers of activity-regulated genes. Exactly how histone acetylation modulates transcription of these genes has remained unknown. We used single-cell in situ transcr...

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Gepubliceerd in:Cell Rep
Hoofdauteurs: Chen, Liang-Fu, Lin, Yen Ting, Gallegos, David A., Hazlett, Mariah F., Gómez-Schiavon, Mariana, Yang, Marty G., Kalmeta, Breanna, Zhou, Allen S., Holtzman, Liad, Gersbach, Charles A., Grandl, Jörg, Buchler, Nicolas E., West, Anne E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376993/
https://ncbi.nlm.nih.gov/pubmed/30699347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.01.032
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