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Stimulus-induced modulation of transcriptional bursting in a single mammalian gene

Mammalian genes are often transcribed discontinuously as short bursts of RNA synthesis followed by longer silent periods. However, how these “on” and “off” transitions, together with the burst sizes, are modulated in single cells to increase gene expression upon stimulation is poorly characterized....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Molina, Nacho, Suter, David M., Cannavo, Rosamaria, Zoller, Benjamin, Gotic, Ivana, Naef, Félix
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870742/
https://ncbi.nlm.nih.gov/pubmed/24297917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312310110
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