Transcriptional burst frequency and burst size are equally modulated across the human genome

Gene expression occurs either as an episodic process, characterized by pulsatile bursts, or as a constitutive process, characterized by a Poisson-like accumulation of gene products. It is not clear which mode of gene expression (constitutive versus bursty) predominates across a genome or how transcr...

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Bibliographic Details
Main Authors: Dar, Roy D., Razooky, Brandon S., Singh, Abhyudai, Trimeloni, Thomas V., McCollum, James M., Cox, Chris D., Simpson, Michael L., Weinberger, Leor S.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2012
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491463/
https://ncbi.nlm.nih.gov/pubmed/23064634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213530109
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