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Transcriptional Bursting Explains the Noise–Versus–Mean Relationship in mRNA and Protein Levels

Recent analysis demonstrates that the HIV-1 Long Terminal Repeat (HIV LTR) promoter exhibits a range of possible transcriptional burst sizes and frequencies for any mean-expression level. However, these results have also been interpreted as demonstrating that cell-to-cell expression variability (noi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Dar, Roy D., Shaffer, Sydney M., Singh, Abhyudai, Razooky, Brandon S., Simpson, Michael L., Raj, Arjun, Weinberger, Leor S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965078/
https://ncbi.nlm.nih.gov/pubmed/27467384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158298
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