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Memory and relatedness of transcriptional activity in mammalian cell lineages

Phenotypically identical mammalian cells often display considerable variability in transcript levels of individual genes. How transcriptional activity propagates in cell lineages, and how this varies across genes is poorly understood. Here we combine live-cell imaging of short-lived transcriptional...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Phillips, Nicholas E., Mandic, Aleksandra, Omidi, Saeed, Naef, Felix, Suter, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6418128/
https://ncbi.nlm.nih.gov/pubmed/30872573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09189-8
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