Cytochrome c-mediated oxidation of hydroethidine and mito-hydroethidine in mitochondria: Identification of homo- and heterodimers.

Here we report that ferricytochrome c (cyt c(3+)) induces oxidation of hydroethidine (HE) and mitochondria-targeted hydroethidine (Mito-HE or MitoSOX ™ Red) forming highly characteristic homo- and heterodimeric products. Using a HPLC-electrochemical (EC) method, several products were detected from c...

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Main Authors: Zielonka, Jacek, Srinivasan, Satish, Hardy, Micael, Ouari, Olivier, Lopez, Marcos, Vasquez-Vivar, Jeannette, Avadhani, Narayan G., Kalyanaraman, B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692199/
https://ncbi.nlm.nih.gov/pubmed/18155177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2007.11.013
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