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HPLC study of oxidation products of hydroethidine in chemical and biological systems: Ramifications in superoxide measurements

Methods for detection and quantitation of hydroethidine (HE) and its oxidation products by HPLC analysis are described. Synthetic methods for preparations of authentic standards (2-hydroxyethidium and diethidium) are provided. Potential applications of the HPLC methods to chemical and biological sys...

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Detalhes bibliográficos
Main Authors: Zielonka, Jacek, Hardy, Micael, Kalyanaraman, B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3375818/
https://ncbi.nlm.nih.gov/pubmed/19026738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.10.031
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