HPLC-based monitoring of products formed from hydroethidine-based fluorogenic probes – The ultimate approach for intra-and extracellular superoxide detection

BACKGROUND: Nearly ten years ago, we demonstrated that superoxide radical anion (O(2)(−̣)) reacts with the hydroethidine dye (HE, also known as dihydroethidium, DHE) to form a diagnostic marker product, 2-hydroxyethidium (2-OH-E(+)). This particular product is not derived from reacting HE with other...

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Hlavní autoři: Kalyanaraman, Balaraman, Dranka, Brian P., Hardy, Micael, Michalski, Radoslaw, Zielonka, Jacek
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858408/
https://ncbi.nlm.nih.gov/pubmed/23668959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2013.05.008
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