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Detection, Characterization, and Decay Kinetics of ROS and Thiyl Adducts of Mito-DEPMPO Spin Trap

We report here the detection and characterization of spin adducts formed from the trapping of reactive oxygen species (superoxide and hydroxyl radicals) and glutathiyl and carbon-centered radicals by a newly synthesized nitrone, Mito-DEPMPO. This is a cationic nitrone spin trap with a triphenyl phos...

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Detalhes bibliográficos
Publicado no:Chem Res Toxicol
Main Authors: Hardy, Micaël, Rockenbauer, Antal, Vásquez-Vivar, Jeannette, Felix, Christopher, Lopez, Marcos, Srinivasan, Satish, Avadhani, Narayan, Tordo, Paul, Kalyanaraman, B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455887/
https://ncbi.nlm.nih.gov/pubmed/17559235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx700101d
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