Doxorubicin Inactivates Myocardial Cytochrome c Oxidase in Rats: Cardioprotection by Mito-Q

Doxorubicin (DOX) is used for treating various cancers. Its clinical use is, however, limited by its dose-limiting cardiomyopathy. The exact mechanism of DOX-induced cardiomyopathy still remains unknown. The goals were to investigate the molecular mechanism of DOX-induced cardiomyopathy and cardiopr...

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Detalhes bibliográficos
Main Authors: Chandran, Karunakaran, Aggarwal, Deepika, Migrino, Raymond Q., Joseph, Joy, McAllister, Donna, Konorev, Eugene A., Antholine, William E., Zielonka, Jacek, Srinivasan, Satish, Avadhani, Narayan G., Kalyanaraman, B.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Membrane
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717244/
https://ncbi.nlm.nih.gov/pubmed/19217856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.10.042
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