Oxidative Stress Induced Mitochondrial Protein Kinase A Mediates Cytochrome C Oxidase Dysfunction

Previously we showed that Protein kinase A (PKA) activated in hypoxia and myocardial ischemia/reperfusion mediates phosphorylation of subunits I, IVi1 and Vb of cytochrome c oxidase. However, the mechanism of activation of the kinase under hypoxia remains unclear. It is also unclear if hypoxic stres...

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Hlavní autoři: Srinivasan, Satish, Spear, Joseph, Chandran, Karunakaran, Joseph, Joy, Kalyanaraman, Balaraman, Avadhani, Narayan G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795003/
https://ncbi.nlm.nih.gov/pubmed/24130844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077129
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