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Hydroethidine- and Mito-SOX-derived red fluorescence is not a reliable indicator of intracellular superoxide formation: Another inconvenient truth

Hydroethidine (or dihydroethidium) (HE) is the most popular fluorogenic probe used for detecting intracellular superoxide radical anion. The reaction between superoxide and HE generates a highly specific red fluorescent product, 2-hydroxyethidium (2-OH-E(+)). In biological systems, another red fluor...

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Detalhes bibliográficos
Main Authors: Zielonka, Jacek, Kalyanaraman, B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587154/
https://ncbi.nlm.nih.gov/pubmed/20116425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2010.01.028
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