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Liaison amid disorder: non-native interactions may underpin long-range coupling in proteins
A lattice-model study of double-mutant cycles published in BMC Structural Biology underscores how interactions in non-native conformations can lead to thermodynamic coupling between distant residues in globular proteins, adding to recent advances in delineating the often crucial roles played by diso...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2689430/ https://ncbi.nlm.nih.gov/pubmed/19344476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/jbiol126 |
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