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pH Dependence of Amide Chemical Shifts in Natively Disordered Polypeptides Detects Medium-Range Interactions with Ionizable Residues

A growing number of natively disordered proteins undergo a folding/binding process that is essential for their biological function. An interesting question is whether these proteins have incompletely solvated regions that drive the folding/binding process. Although the presence of predominantly hydr...

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Detalhes bibliográficos
Main Authors: Pujato, Mario, Bracken, Clay, Mancusso, Romina, Cataldi, Marcela, Tasayco, María Luisa
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366825/
https://ncbi.nlm.nih.gov/pubmed/16113108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.060384
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