SCF(βTRCP)Controls Oncogenic Transformation and Neural Differentiation Through REST Degradation

The transcription factor REST/NSRF (RE1-Silencing Transcription Factor) is a master repressor of neuronal gene expression and neuronal programs in non-neuronal lineages1−3. Recently, REST was identified as a human tumor suppressor in epithelial tissues4, suggesting that REST regulation may have impo...

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Detalhes bibliográficos
Main Authors: Westbrook, Thomas F., Hu, Guang, Ang, Xiaolu L., Mulligan, Peter, Pavlova, Natalya N., Liang, Anthony, Leng, Yumei, Maehr, Rene, Shi, Yang, Harper, J. Wade, Elledge, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688689/
https://ncbi.nlm.nih.gov/pubmed/18354483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06780
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