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Synthetic Small-Molecule Prohormone Convertase 2 Inhibitors

The proprotein convertases are believed to be responsible for the proteolytic maturation of a large number of peptide hormone precursors. Although potent furin inhibitors have been identified, thus far, no small-molecule prohormone convertase 1/3 or prohormone convertase 2 (PC2) inhibitors have been...

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Bibliografische gegevens
Hoofdauteurs: Kowalska, Dorota, Liu, Jin, Appel, Jon R., Ozawa, Akihiko, Nefzi, Adel, Mackin, Robert B., Houghten, Richard A., Lindberg, Iris
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Pharmacology and Experimental Therapeutics 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684913/
https://ncbi.nlm.nih.gov/pubmed/19074544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.051334
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