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Synthetic Small-Molecule Prohormone Convertase 2 Inhibitors
The proprotein convertases are believed to be responsible for the proteolytic maturation of a large number of peptide hormone precursors. Although potent furin inhibitors have been identified, thus far, no small-molecule prohormone convertase 1/3 or prohormone convertase 2 (PC2) inhibitors have been...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Pharmacology and Experimental Therapeutics
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2684913/ https://ncbi.nlm.nih.gov/pubmed/19074544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.051334 |
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