Alternative preparation of inclusion bodies excludes interfering non-protein contaminants and improves the yield of recombinant proinsulin

Por Mackin, Robert B.
Publicado no MethodsX (2014)

Synthetic Small-Molecule Prohormone Convertase 2 Inhibitors

Por Kowalska, Dorota, Liu, Jin, Appel, Jon R., Ozawa, Akihiko, Nefzi, Adel, Mackin, Robert B., Houghten, Richard A., Lindberg, Iris
Publicado em 2009

Solution Structure of Proinsulin: CONNECTING DOMAIN FLEXIBILITY AND PROHORMONE PROCESSING

Por Yang, Yanwu, Hua, Qing-xin, Liu, Jin, Shimizu, Eri H., Choquette, Meredith H., Mackin, Robert B., Weiss, Michael A.
Publicado em 2010

Crystal Structure of a “Nonfoldable” Insulin: IMPAIRED FOLDING EFFICIENCY DESPITE NATIVE ACTIVITY

Por Liu, Ming, Wan, Zhu-li, Chu, Ying-Chi, Aladdin, Hassan, Klaproth, Birgit, Choquette, Meredith, Hua, Qing-xin, Mackin, Robert B., Rao, J. Sunil, De Meyts, Pierre, Katsoyannis, Panayotis G., Arvan, Peter, Weiss, Michael A.
Publicado em 2009

An Achilles' Heel in an Amyloidogenic Protein and Its Repair: INSULIN FIBRILLATION AND THERAPEUTIC DESIGN

Por Yang, Yanwu, Petkova, Aneta, Huang, Kun, Xu, Bin, Hua, Qing-xin, Ye, I-Ju, Chu, Ying-Chi, Hu, Shi-Quan, Phillips, Nelson B., Whittaker, Jonathan, Ismail-Beigi, Faramarz, Mackin, Robert B., Katsoyannis, Panayotis G., Tycko, Robert, Weiss, Michael A.
Publicado em 2010