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Inhibitor screening of proprotein convertases using positional scanning libraries

Proprotein convertases represent an important class of biosynthetic enzymes that are increasingly viewed as targets for therapeutic approaches to infection, cancer and potentially endocrine disorders. The identification of potent inhibitors can be accomplished by screening synthetic combinatorial li...

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Detalhes bibliográficos
Main Authors: Lindberg, Iris, Appel, Jon R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845831/
https://ncbi.nlm.nih.gov/pubmed/21805241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-204-5_7
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