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Cdk3-Mediated c-Jun Phosphorylation at Ser63 and Ser73 Enhances Cell Transformation

c-Jun is a component of the activator protein-1 (AP-1) complex, which plays a crucial role in the regulation of gene expression, cell proliferation and cell transformation as well as cancer development. Herein, we found that Cdk3, but not Cdk2 or JNK, is a novel kinase of c-Jun induced by stimulatio...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Cho, Yong-Yeon, Tang, Faqing, Yao, Ke, Lu, Chengrong, Zhu, Feng, Zheng, Duo, Pugliese, Angelo, Bode, Ann M., Dong, Zigang
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2684448/
https://ncbi.nlm.nih.gov/pubmed/19118012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3125
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