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CSK-Mediated c-Jun Phosphorylation Promotes c-Jun Degradation and Inhibits Cell Transformation

The oncoprotein c-Jun is a component of the activator protein-1 (AP-1) transcription factor complex, which is involved in cellular proliferation, transformation and death. The stabilization of c-Jun is critically important for its function. Phosphorylation of c-Jun by c-Jun N-terminal kinase 1 (JNK1...

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Detalhes bibliográficos
Main Authors: Zhu, Feng, Choi, Bu Young, Ma, Wei-Ya, Zhao, Zhongliang, Zhang, Yiguo, Cho, Yong Yeon, Choi, Hong Seok, Imamoto, Akira, Bode, Ann M., Dong, Zigang
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2239244/
https://ncbi.nlm.nih.gov/pubmed/16740711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-05-4466
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