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Phosphorylation of Histone H3 at Serine 10 is Indispensable for Neoplastic Cell Transformation

Very little is known about the role of histone H3 phosphorylation in malignant transformation and cancer development. Here, we examine the function of H3 phosphorylation in cell transformation in vivo. Introduction of small interference RNA (siRNA)-H3 into JB6 cells resulted in decreased EGF-induced...

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Detalhes bibliográficos
Main Authors: Choi, Hong Seok, Choi, Bu Young, Cho, Yong-Yeon, Mizuno, Hideya, Kang, Bong Seok, Bode, Ann M., Dong, Zigang
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2227263/
https://ncbi.nlm.nih.gov/pubmed/15994958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-05-0197
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