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Phosphorylation of Histone H3 at Serine 10 is Indispensable for Neoplastic Cell Transformation
Very little is known about the role of histone H3 phosphorylation in malignant transformation and cancer development. Here, we examine the function of H3 phosphorylation in cell transformation in vivo. Introduction of small interference RNA (siRNA)-H3 into JB6 cells resulted in decreased EGF-induced...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2005
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2227263/ https://ncbi.nlm.nih.gov/pubmed/15994958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-05-0197 |
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