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Phosphorylation of Histone H3 at Serine 10 is Indispensable for Neoplastic Cell Transformation

Very little is known about the role of histone H3 phosphorylation in malignant transformation and cancer development. Here, we examine the function of H3 phosphorylation in cell transformation in vivo. Introduction of small interference RNA (siRNA)-H3 into JB6 cells resulted in decreased EGF-induced...

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Autors principals: Choi, Hong Seok, Choi, Bu Young, Cho, Yong-Yeon, Mizuno, Hideya, Kang, Bong Seok, Bode, Ann M., Dong, Zigang
Format: Artigo
Idioma:Inglês
Publicat: 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2227263/
https://ncbi.nlm.nih.gov/pubmed/15994958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-05-0197
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