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Cdk3-Mediated c-Jun Phosphorylation at Ser63 and Ser73 Enhances Cell Transformation
c-Jun is a component of the activator protein-1 (AP-1) complex, which plays a crucial role in the regulation of gene expression, cell proliferation and cell transformation as well as cancer development. Herein, we found that Cdk3, but not Cdk2 or JNK, is a novel kinase of c-Jun induced by stimulatio...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2684448/ https://ncbi.nlm.nih.gov/pubmed/19118012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3125 |
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