Nalaganje...

CYP2C9 Amino Acid Residues Influencing Phenytoin Turnover and Metabolite Regio- and Stereochemistry

Phenytoin has been an effective anticonvulsant agent for over 60 years, although its clinical use is complicated by nonlinear pharmacokinetics, a narrow therapeutic index, and metabolically based drug-drug interactions. Although it is well established that CYP2C9 is the major cytochrome P450 enzyme...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Mosher, Carrie M., Tai, Guoying, Rettie, Allan E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Pharmacology and Experimental Therapeutics 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683772/
https://ncbi.nlm.nih.gov/pubmed/19258521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.150706
Oznake: Označite
Brez oznak, prvi označite!