WISP1, a Pro-mitogenic, Pro-survival Factor, Mediates Tumor Necrosis Factor-α (TNF-α)-stimulated Cardiac Fibroblast Proliferation but Inhibits TNF-α-induced Cardiomyocyte Death

WNT1-inducible signaling pathway protein-1 (WISP1), a member of the CYR61/CTGF/Nov family of growth factors, can mediate cell growth, transformation, and survival. Previously we demonstrated that WISP1 is up-regulated in post-infarct heart, stimulates cardiac fibroblast proliferation, and is induced...

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Detalhes bibliográficos
Main Authors: Venkatachalam, Kaliyamurthi, Venkatesan, Balachandar, Valente, Anthony J., Melby, Peter C., Nandish, Sailesh, Reusch, Jane E. B., Clark, Robert A., Chandrasekar, Bysani
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682890/
https://ncbi.nlm.nih.gov/pubmed/19339243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M809757200
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